Displacement chromatography on synthetic ion-exchange resins. 1. Separation of organic bases and amino-acids using cation-exchange resins.

9. Accumulation of glutamate also occurred in isolated kidney cortex, spleen, lung and chorion. Six other tissues examined maintained a concentration gradient between tissue and medium, but did not increase the glutamate concentration above the original level. 10. It is pointed out that tissue slices afford a system in which problems of permeability and storage can be studied under controlled conditions. The permeability of brain tissue for glutamate is controlled by energy-giving metabolic processes.